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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a86d1209a3568e690a733922d9855c39dbaa5d95b156867de93e9bc5f592c9f' 
  AND token = 'LdmLvO/4VVAqpdmsZwp3ikQZxH7P2/ihhTd2ldqo0WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}