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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24226fb9e3e669b9651fde2cbe379ea82548cc75a2546220cc4165dd2cdb2934' 
  AND token = '+4xk1CWbqDBDSVIYbHFqbUhaoO5SlfV2RLexHmubjHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}