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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ec796b19fa5964e9d5464331116b62efd5fd6ecec8d0c5e11b13ed2a19ed49' 
  AND token = '2EBosnFBYeUhcEB3p+si0c5zZL2+06D3JrPFWGHv+EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}