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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a7eae8b551f8526f8cb7277f6bfa9ce4f4389f34d470f7f3f1721bad9407be' 
  AND token = 'qg5lWKMOHhyfULVnUiOb0TXla/XxgkuZN3cYV2aS0eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}