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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07fb4d3a4cfcec14e5428b417f4ea3e78c8da19ce32b08f3737fdac155e4806c' 
  AND token = 'Y1qXeQ5/8Oc3zAqusa1F1LDOG8NOYyvFVB0iWw9r7Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}