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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f59c7789c02eea51823cc60e4285dda01b8ff27cfd2295a1ce1d40c4e5f85da' 
  AND token = 'up4v43ftBQTBmjPnajJvvpfq8eLmk9aDDjCM+o+hkJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}