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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7351d04dbb112c4f5f1c9406a19fd22aab5de73067dda5e4cadb5be323b3ffee' 
  AND token = '0/dVFJ38pFBEsJpPKPxsibCpaOH2crHAwUHEaKV7ZIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}