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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccc091556830b381829aaf351c4cb688637db4bc53ae1e12a10c998d4a20d07' 
  AND token = 'iten7pkEo13uomxVq2E37MnjdKV/cDtTB1ZV2Cas9G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}