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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab41a022c429563a61eb46bee9b926965ca26c3248fd37f6a5b3213afcb58fd' 
  AND token = 'fv6sKULYlAS4k905/ZL+RvJfjf7d8b2w7NRxKTDglSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}