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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0666278bb0b01f15900842923ff4c92c4f4bace3bd7b8efc4e793fd4d62ebd8' 
  AND token = '6+MYNL8/2Gd0LHMchN+IAf077fsK0mBu8F8LmG7MqxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}