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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811bbde8d5e37b7a5aa9e348d2b7f1744bf3b605e7e2b88c619235123b48a321' 
  AND token = 'lZyODWcJixio114/bctJIpQ+4HOoH+eYCaZAZBFEy7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}