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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0f2eb0d685a95dbd345dc90083f6f5e5c8a952f165c326470abaee2d2a1bb4' 
  AND token = 'HpHwkdv80UuPOOcVjaoAzM0WwOlNDvoHpTJPmT4/YBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}