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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580d82ba934ed4180104ad2c8e710a4b41207f0e12470d28e55e4d1f5f65c1cf' 
  AND token = 'z+DvuOhKkFhsAa44nIVHhz/+iVIy3O5awh7fIQpl2sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}