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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00bbc3a872234dfaf2a3523c86adfdf336b3e16b416b0fdad025537aa27d1ab' 
  AND token = 'yGwjgcRXXR2sgynGDv63mSQpMsWWTvAQ0byeqsa/OF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}