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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721066b333e5b93fb2d3961d03a146aea424ee80c7a461981e15ea409ba48fce' 
  AND token = 'dNYrsPGsTQbJ1HBbMiTuLTGAa9rMHCzGR4x4Cr4no3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}