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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0991b50ba858a65aa50763358fed42b96c3b22e1de28b475715bb1b88ae3c55' 
  AND token = 'vDXx3prAGRqkZ5zMVH03ilcJgkp8qvRx2o7XEayqyxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}