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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e0f49990bef34b34a0e7fc51d4252161774e65f903b160214d46a766baa6de' 
  AND token = 'c1P0hwdS/kDVrZI+CLGBj/7a6japOktw2lb2saTR5Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}