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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb10c2d35c8e275376b2cd6c380a5d0c82e781d22d32b1545635f14f552928f' 
  AND token = 'U/C0UfOsLCXj/ZtL1hiTynxhy6KEqAyD4vpUuf3ubBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}