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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21e20793f1457d2225e1e4356c03735110a8fbe98a9d7a679a63a5fde03515d' 
  AND token = '9oLNo+uxffYwn3npGrZvOYxKJu7n26klcg19HVss74c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}