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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa4260163db9e28a45dbb14f52058001946b0eb2841e2da3bcfed993eaaeb1f' 
  AND token = 'rMfpHUTN593FaXhH9JthveKleIoVG/7rbdPJzSAozHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}