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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6d1ee8ea94038d9b83db71b61469f754b6afd930a1a7df4b4cd7a10c9ff0f0' 
  AND token = 'lW4wSxGFV1LP3xSqa4r/B5FAIvzFB/BjPLxFF6OgMnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}