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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '856501b4b2492b440e21887a9e518a3623454eb839025a1955468f33865166cb' 
  AND token = 'OrLFQe/YOmouN+6R5WhDbly/sFqTIOqJMD6XwjCB/Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}