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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b655844af3cbd27f868e8507a3a6e52d08eec5489b1a09cce33bd90ee5a0d7e6' 
  AND token = 'E+oF+dCPPpYCN79LcthXtI+tX3+/9PggWiD6Dl+d7Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}