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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de8d45e921596296c65e10c97ccb327989a1a3cdc33a962b688754ea1ec769a' 
  AND token = 'T1eKHu7oziCBVe3fDEhpQ6JW4YvBcQDyc2+ijTSO2D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}