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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6945685eba9ac6611c81bcd910b56fe0dac25a4a9aee20ef890627bc0443ac4a' 
  AND token = 'A3ccCBrRo0aK0l/UbhhBmoskQfhrWpQkBaiDTZfmrpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}