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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac1ac45fa5569385e319932b629b7186b178bec2c5a0bf2cd9ed85116bd0ceb' 
  AND token = 'vgYOBtcF4+oLbWP58gJTBDRSxn68bFtTevtrar1jDGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}