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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b397596ea8f5f874e79effa9da4cd0be39a69321810d5101ad6b30072659d595' 
  AND token = 'BX29YXxifWjP8BoP5RsCHZs4C9dQL/AeoCJjNE/GyLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}