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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390b057a1762708e384076d14054da345bad228f3520cf28cd29010472785b14' 
  AND token = 'V2tg4DB1Fi98LwI3qj36EOLUDH2L6VRxfyCSHiU4ObU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}