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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b644c6357722ab28bc3f55271d75c1efb5da51debee38e79c41be7a5c503977f' 
  AND token = 'VShRSo7MDZePEjCYYHR3zFUb4lh5enHNXvz6tfCr8aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}