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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aaf781ae6758979d4dfb8f4ca6a94b7cb3d04d8647a185c210a8e9697980eab' 
  AND token = 'pJyPOLawMZeYNRO7qoAwjhOLvp7mVxhoRFc0LFrOKt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}