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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b10397343319f855c51c0f48b6594578da3d0d37d547eb1ad808c7571ee540' 
  AND token = '++tJF9lFjMRCaMaGw3h2jKdNN5d0la5xoKc5VV5lI+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}