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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d29f717b1d30515c046641be4c91c8fbf1c7a6347c0fb9448d16481d6cc261' 
  AND token = '6yYquMIyFSq7YynQc+qLVlV1wiiFsV/VDJ6WIvuMBfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}