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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143d99c8796cf0fa6ed76a6fc295898ebb3d5cbc0850a051d0f79010911af705' 
  AND token = '7y4Tm/2qXr0CuvVkIvmzZ16gZrAJAcRmG5I48cJwTdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}