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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fd0a303d1ed238b69d56024318b69de190bda071e2617a0bf7dcb4ec7ac6ee' 
  AND token = 'j/dnwmIfuuF/hyhAfGMcLkmTq2VpgE62ZkD5p/8INh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}