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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15c0284cb014b04535bc456a932040ad545051ebedd778a8c9dd9985ee0ae704' 
  AND token = 'l432DRtiFkPtup7v8FcL6OJktD33vvkEFlmmO6GcoYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}