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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8f194e38a93e6d9ec322205e434b49ed280c9ab305052d395be4d3535d5157' 
  AND token = 'Z11LY6ThTWu6xsDFnTx9ikeFSCVb+MOSj2kJMZ+v28s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}