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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab3343a636fca168c93863217d7ce121b0b00ebce7e294a9d69aacd59ed8a5d1' 
  AND token = '/s8mbVR6xERtzY+CmHjD5xm3z2vizjdv8RugrKS1ZZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}