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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d662ec2ae9221df1248b8f78891e040cf8273e2c704870fbafe1c589fe4dec2' 
  AND token = '/6cFAuq4g/0E8c/H4foQzI8j8DNFTx/WPgAygD+9Szg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}