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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2472473da0ffc1e195a185c29bbb7ec39b14df90e19408fdbb4ccaf79339e90f' 
  AND token = 'w/c2nFWMuF0khKUMoxkc3d36czw6BR3K6EA9ZN/OyFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}