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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e26ea3c23dab535b75d6c463d135ce273b88ce797646f592358baace01d706' 
  AND token = '6BZzF4obvDeQCID0pV6G8WtYRSMJ1UKYZ7C7PIPyA6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}