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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74defa34ea95e4689e22d4e4c4c5ffdf65a3106aedac0dfa2e6f7ef06124c34a' 
  AND token = 'SyZRTzlxgJ9fgifh6D2GVV/r/nEst8axL2v12Jnbeno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}