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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0964a10ad04c52d230cb9d2ea5caeead9f16817ff596fc361d1995e1eda28d6' 
  AND token = 'TCz1gFNVag0ZLt11QrmkcrF8qA2p1Hdyd0Z3NF27clc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}