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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b0464aeef0f101e660b6f7ffbccb93b86876eb93141c9547eda5db95a10e60' 
  AND token = 'DSJ8ouGIZmIzOJhj7e7xj2eOdEOX98k+/04OZqCQCNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}