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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122ed5fcd8a35d253580da41de69e50d169367db4913d0452949321a7c2a50c4' 
  AND token = 'L3PPSZs4g8Wt3W/qRw/3mvliMMZlfIPEgZuV/VGgJW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}