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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215fcb5396b3d8b71ab113c6da39ed7b04db36a011a02cd647146e6c5db982bd' 
  AND token = 'XleTGeboZIc4LwvLZCQCbnAJVn9IdYLyII3sj6CKhVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}