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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953cfe23ef74b3a0fa7126eabf24940aa817b40c996caa1f611eadce1661e6c1' 
  AND token = '1c6AQ7DoiA2KIWpxonaqKTaKiW89X25JRCgPvp2+kyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}