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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '662993b2bdd7cf2174ca823a34635233e87b66d591cc1b19d4b167bd12738ad4' 
  AND token = 'nWjEe+ITvBDXi7PuSiR5xSj270jfnU0n+CF4FwTPXq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}