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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52495994355c46ec68a6c179b2efe576e358812ea4f0c998a8e7e582819ea976' 
  AND token = '4rlMkhhhXUqmWYiYm+P6P50IIuEGJvJFtfs1vBMNp4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}