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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddaa2ad604bfa2245767478c677d3b408efa9312adaef433ea5693741475c609' 
  AND token = 'QVYcuwFnK2Mum2qoeU4wE16lcKbY0zPYSE0y3Hfnrt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}