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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55c269e409ab84c2d29197add1bc40eae028135bafe48854386507ece5d3aa4' 
  AND token = 'zOQ4EXz/SHwErzWMkEmINSAZ6zMmCCZIsCPbMxNK2UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}